pksensi 1.2.2 2021-07-04

  • Add more flexible parallel method (solve_mcsim)
  • Fix error in previous version

pksensi 1.2.1 2021-06-18

pksensi 1.2.0 2020-06-15

  • update the route to load example model
  • update the default MCSim version to 6.2.0
  • Switch the contact mail to

pksensi 1.1.7 2020-05-08

pksensi 1.1.6 2020-05-05

  • Improved heat_check() to only show influential parameters as default
  • Updated check() to return the SI and CI in a list

pksensi 1.1.5 2020-02-05

  • solve_mcsim(): extend the flexible for the model in subfolder
  • Update the vignettes (add deSolve modeling example)

pksensi 1.1.4 2019-09-19

pksensi 1.1.3 2019-08-20

pksensi 1.1.2 2019-06-30

pksensi 1.1.1 2019-05-29

Fix Bug:

  • Add rtol and atol in solve_mcsim()
  • Switch default compiler from Clang to GCC in MacOS
  • Fix the mName problem under Windows environment in solve_mcsim()

Update vignette

  • Remind to set the mxstep to 5000 in APAP-PBPK example
  • Add note to APAP vignette (Set atol and rtol)

Update function

  • mcsim_version() can work in MCSim_under_R
  • Stop the function when compile error in compile_model()
  • Revise the default name of output to “simmc.out” and “setpts.out” in solve_mcsim()

pksensi 1.1.0 2019-05-12

Fix Bug:

Update function:


  • Update the default MCSim version to version = 6.1.0 in install_mcsim()
  • Adopt the name of model file (“model.R.exe”) to MCSim_under_R project


  • Change assignment n to monte_carlo in solve_mcsim()
  • Revise the default name of output to “sim.out” and “setpoint.out” in solve_mcsim()
  • Add solving message to track time spend in solve_mcsim()
  • Add assignment tell = T to automatically combine the output y in decoupling simulation x in solve_fun() and solve_mcsim()


  • Transfer the log-transformed value to natural scale in pksim()
  • Revise the discrete time condition to length(times) < 16 in heat_check()

pksensi 1.0.1 2019-01-29

New vignette:

  • Add “PBTK 1-compartment model”
  • Add “Acetaminophen-PBPK model”

New example:

New function:

NEW dataset:

  • Add APAP dataset

Fix Bug:

Update function:


pksensi 1.0.0 2018-10-30

  • Initial release in CRAN